I'd love to see villains based on real people.
Scott Baio, for example. Most people say HAPPY DAYS jumped the shark when Fonzie...well, Jumped the Shark. But I knew it was when Chachi bobbed in with his . At that moment, deep down, I realized what a true sociopath Scott Baio is. Can you imagine the cover of such an issue, with Chachi planting his foot on Superman's neck, his eyes aglee with manical fire, and his hand smashing a globe, with an electric bubble near his mout that reads:
"Soon, I'll be Charles in Charge...of THE WORLD! BWA-hahahaha!"
He's not serious enough to pull it off. Observe:
http://www.goats.com/comix/9905/goats990527.gifAnd besides, Scott Baio is a Marvel character, landlord to Kraven's son in the "Get Kraven" miniseries. For there to be a crossover story with him, we'd have to find some sort of equivalent malevolence in the DC universe -- perhaps Zan the waterboy from the Wonder Twins.